Potassium and Phosphorus Replacement
Intravenously

Normal Serum Phosphate:
    Adult: 3.0-4.5 mg/dL (1.0-1.5nM/L)
    Pediatric: 4.0-7.0 mg/dL (1.3-2.3 mM/L)

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Potassium (K+), Phosphorus (PO4),
or
Potassium and Phosphate Replacement

Serum PO4 (mg/dL)→ <1.0 1.0-1.5 1.6-1.9 2.0-2.5 2.6-2.9
  For Phosphorus Only Replacement Give KPO4
Note: Weight based
0.4mM/Kg
=0.58mEq/Kg of KPO4
0.35mM/Kg
=0.51mEq/Kg of KPO4
0.3mM/Kg
=0.44mEq/Kg of KPO4
0.25mM/Kg
=0.36mEq/Kg of KPO4
0.2mM/Kg
=0.29mEq/Kg of KPO4
Serum K+
(mEq/L)
For Potassium Only Replacement Give KCl To Replace both Potassium and Phosphorus Simultaneously
Based on the K+ and PO4 levels noted on the top and side column and row values respectively.
Note: this is not weight based in the cells below.
3.6-3.9 20 mEq 30mM NaPO4
+
20mEq KCl
20mM NaPO4
+
20mEq KCl
22mEq KPO4 14.6mEq KPO4
+
5mEq KCl
8.8mEq KPO4
+
10mEq KCl
3.4-3.5 30 mEq 30mM NaPO4
+
30mEq KCl
30mEq KPO4 22mEq KPO4
+
8mEq KCl
14.6mEq KPO4
+
15mEq KCl
8.8mEq KPO4
+
20mEq KCl
3.1-3.3 40 mEq 40 mEq KPO4
 
30mEq KPO4
+
10mEq KCl
22mEq KPO4
+
18mEq KCl
14.6mEq KPO4
+
25mEq KCl
8.8mEq KPO4
+
31mEq KCl
2.6-3.0 50 mEq 44mEq KPO4
+
6mEq KCl
29.3mEq KPO4
+
20mEq KCl
22mEq KPO4
+
28mEq KCl
14.6mEq KPO4
+
35mEq KCl
8.8mEq KPO4
+
41mEq KCl
2.3-2.5 60 mEq 44mEq KPO4
+
16mEq KCl
29.3mEq KPO4
+
30mEq KCl
22mEq KPO4
+
38mEq KCl
14.6mEq KPO4
+
45mEq KCl
8.8mEq KPO4
+
51mEq KCl
<2.3 60 mEq Same as Above        
Color Code for Administration Rate: Cannot exceed 6 mEq/Hour of K+ without Telemetry Monitoring
 

20-30 mEq of K+: Would generally not exceed 200 mL/Hour

 

40-50 mEq of K+: Would generally not exceed 125 mL/Hour

 

60 mEq of K+: Would not exceed 100 mL/Hour

Notes:
    1. Inorganic Phosphorus exists in the body as the mono- and di-basic forms, the relative proportions of which are pH dependent. It is therefore preferable to report concentrations as mg/dL or mM/L, rather than mEq/L.
    2. Always be cautious giving KPO4 to patients with significant renal failure. Think twice about what you are doing and monitor them carefully.

Abbreviations:
    K+ = Potassium
    Kg = kilogram
    KPO4 = Potassium Phosphate
    L = liter
    mEq = milliequivalents
    mEq/Kg = milliequivalents per kilogram
    mEq/L= milliequivalents per Liter
    mg/dL = milligram per deciliter
    ml = milliliters
    mM = millimoles
    mM/Kg = millimoles per kilogram
    NaPO4 = Sodium Phosphate
    PO4 = Phosphate

A special thanks to Myrna and the pharmacists of Silverton Hospital for this very useful table, pardon my slight modifications.

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